Research Data Leeds Repository

Irradiation of acellular porcine superflexor tendons.

Edwards, Jennifer and Herbert, Anthony and Manfield, Iain and Fisher, John and Ingham, Eileen (2015) Irradiation of acellular porcine superflexor tendons. University of Leeds. [Dataset] https://doi.org/10.5518/30

Dataset description

Data on the biological and biomechanical properties of acellular porcine superflexor tendons grafts following irradiation: example histology and cytotoxicity images; biomechanical testing data (ultimate tensile strength, failure strain, Young's modulus); collagen and denatured collagen content; thermal stability measurements.

Keywords:	Anterior cruciate ligament, knee reconstruction, porcine, decellularisation, sterilisation, acellular graft
Subjects:	H000 - Engineering > H100 - General engineering > H160 - Bioengineering, biomedical engineering & clinical engineering > H161 - Biomaterials H000 - Engineering > H100 - General engineering > H160 - Bioengineering, biomedical engineering & clinical engineering > H162 - Biomechanics (including fluid & solid mechanics)
Divisions:	Faculty of Biological Sciences > Institute of Medical and Biological Engineering Faculty of Engineering > Institute of Medical and Biological Engineering Faculty of Engineering > School of Mechanical Engineering > Institute of Medical and Biological Engineering
Related resources:	Location Type https://doi.org/10.1002/jbm.b.33786 Publication
License:	Creative Commons Attribution 4.0 International (CC BY 4.0)
Date deposited:	13 Oct 2016 08:41
URI:	http://archive.researchdata.leeds.ac.uk/id/eprint/87
Additional details Additional details Creators: Creators ORCID Other ID Email Primary affiliation Primary affiliation ID Primary affiliation ID type Secondary affiliation Secondary affiliation ID Secondary affiliation ID type Edwards, Jennifer https://orcid.org/0000-0003-4152-6140 Herbert, Anthony https://orcid.org/0000-0002-6527-2205 Manfield, Iain https://orcid.org/0000-0003-3765-0325 Fisher, John https://orcid.org/0000-0003-3833-3700 Ingham, Eileen https://orcid.org/0000-0002-9757-3045 Type of data: Dataset Research funders: ERC Grant numbers: 267114REGENKNEE Publication date: 2015 Resource language: English Metadata language: English Research project title: REGENKNEE Publisher: University of Leeds Copyright Holders: University of Leeds Contact Email Address: E.ingham@leeds.ac.uk Last Modified: 07 Feb 2019 10:04

Files

Documentation

Key to sample/group numbers [342B] Key to sample/group numbers [342B] Key to sample/group numbers [342B] Visible to: Anyone File name: Sample_group_and_number_key.txt Content type: Documentation Description: Key listing the sterilisation groups for different sample numbers Mime-Type: text/plain License: Creative Commons Attribution 4.0 International (CC BY 4.0) File size: 342B

Data

Collagen and Denatured collagen content [144kB] Collagen and Denatured collagen content [144kB] Collagen and Denatured collagen content [144kB] Visible to: Anyone File name: sSFT_HYP_DNC_all_data.xlsx Content type: Data Description: Details of the tissue weights and solution volumes used in collagen and denatured collagen assays. Includes calculation of hydroxyproline content. Mime-Type: application/vnd.openxmlformats-officedocument.spreadsheetml.sheet License: Creative Commons Attribution 4.0 International (CC BY 4.0) File size: 144kB

Collagen and Denatured collagen content - raw data [16kB] Collagen and Denatured collagen content - raw data [16kB] Collagen and Denatured collagen content - raw data [16kB] Visible to: Anyone File name: HYP_DNC_raw_data_files.zip Content type: Data Description: Raw data from spectophotometer for collagen and denatured collagen quantification as .txt files, including a description of the samples containted in each dataset Mime-Type: application/zip License: Creative Commons Attribution 4.0 International (CC BY 4.0) File size: 16kB

Transition temperatures comparison [365B] Transition temperatures comparison [365B] Transition temperatures comparison [365B] Visible to: Anyone File name: DSC_DSF_Comparison.txt Content type: Data Description: Comparison of differential scanning calorimetry and differential scanning fluorimetry transition temperatures for sterilised superflexor tendon Mime-Type: text/plain License: Creative Commons Attribution 4.0 International (CC BY 4.0) File size: 365B

Transition temperatures comparison - DSC [636B] Transition temperatures comparison - DSC [636B] Transition temperatures comparison - DSC [636B] Visible to: Anyone File name: sSFT_DSF_Data.txt Content type: Data Description: Thermal transition temperatures of sterilised acellular porcine superflexor tendon (ankle region) as measured by differential scanning caloimetry Mime-Type: text/plain License: Creative Commons Attribution 4.0 International (CC BY 4.0) File size: 636B

Biomechanical testing [19kB] Biomechanical testing [19kB] Biomechanical testing [19kB] Visible to: Anyone File name: Mechanical_failure_data.xlsx Content type: Data Description: Vaules of Ultimate Tensile Strength, Failure Strain and Young's Modulus for acellular porcine superflexor tendons following irradiation Mime-Type: application/vnd.openxmlformats-officedocument.spreadsheetml.sheet License: Creative Commons Attribution 4.0 International (CC BY 4.0) File size: 19kB

Histological data [13kB] Histological data [13kB] Histological data [13kB] Visible to: Anyone File name: Microscopy_observation_summary.docx Content type: Data Description: Summary of the observations made across all tendon groups Mime-Type: application/vnd.openxmlformats-officedocument.wordprocessingml.document License: Creative Commons Attribution 4.0 International (CC BY 4.0) File size: 13kB

Histological images [686MB] Histological images [686MB] Histological images [686MB] Visible to: Anyone File name: Histology_by_sterilisation_treatment.zip Content type: Data Description: Example images from each sample group and each timepoint. Note: more slides were viewed than were captured as histological images. Observations were recorderd ina lab book and are summarised in the Microscopy_observation_summary.docx document. Mime-Type: application/zip License: Creative Commons Attribution 4.0 International (CC BY 4.0) File size: 686MB

Cytotoxicity testing [14kB] Cytotoxicity testing [14kB] Cytotoxicity testing [14kB] Visible to: Anyone File name: Cytoxicity_observations.xlsx Content type: Data Description: Observations from contact cytotoxicity testing of all tendons Mime-Type: application/vnd.openxmlformats-officedocument.spreadsheetml.sheet License: Creative Commons Attribution 4.0 International (CC BY 4.0) File size: 14kB

Cytotoxicity testing - images [721MB] Cytotoxicity testing - images [721MB] Cytotoxicity testing - images [721MB] Visible to: Anyone File name: Biocompatibility.zip Content type: Data Description: Representative images of cyotoxicity testing Mime-Type: application/zip License: Creative Commons Attribution 4.0 International (CC BY 4.0) File size: 721MB