Research Data Leeds Repository

Citation

Edwards, Jennifer and Herbert, Anthony and Manfield, Iain W. and Fisher, John and Ingham, Eileen (2015) Irradiation of acellular porcine superflexor tendons. University of Leeds. [Dataset] https://doi.org/10.5518/30

Dataset description

Data on the biological and biomechanical properties of acellular porcine superflexor tendons grafts following irradiation: example histology and cytotoxicity images; biomechanical testing data (ultimate tensile strength, failure strain, Young's modulus); collagen and denatured collagen content; thermal stability measurements.

Keywords:	Anterior cruciate ligament, knee reconstruction, porcine, decellularisation, sterilisation, acellular graft
Subjects:	H000 - Engineering > H100 - General engineering > H160 - Bioengineering, biomedical engineering & clinical engineering > H161 - Biomaterials H000 - Engineering > H100 - General engineering > H160 - Bioengineering, biomedical engineering & clinical engineering > H162 - Biomechanics (including fluid & solid mechanics)
Divisions:	Faculty of Biological Sciences > Institute of Medical and Biological Engineering Faculty of Engineering and Physical Sciences > Institute of Medical and Biological Engineering Faculty of Engineering and Physical Sciences > School of Mechanical Engineering > Institute of Medical and Biological Engineering
Related resources:	Location Type https://doi.org/10.1002/jbm.b.33786 Publication https://eprints.whiterose.ac.uk/105217/ Publication
License:	Creative Commons Attribution 4.0 International (CC BY 4.0)
Date deposited:	13 Oct 2016 08:41
URI:	https://archive.researchdata.leeds.ac.uk/id/eprint/87
Additional details Additional details Creators or authors: Creators ORCID Other ID Email Primary affiliation Primary affiliation ID Primary affiliation ID type Secondary affiliation Secondary affiliation ID Secondary affiliation ID type Edwards, Jennifer https://orcid.org/0000-0003-4152-6140 University of Leeds https://ror.org/024mrxd33 ror Herbert, Anthony https://orcid.org/0000-0002-6527-2205 University of Leeds https://ror.org/024mrxd33 ror Manfield, Iain W. https://orcid.org/0000-0003-3765-0325 University of Leeds https://ror.org/024mrxd33 ror Fisher, John https://orcid.org/0000-0003-3833-3700 University of Leeds https://ror.org/024mrxd33 ror Ingham, Eileen https://orcid.org/0000-0002-9757-3045 University of Leeds https://ror.org/024mrxd33 ror Type of data: Dataset Research funders: ERC Grant numbers: 267114REGENKNEE Publication date: 2015 Resource language: English Metadata language: English Research project title: REGENKNEE Publisher: University of Leeds Copyright holders: University of Leeds Contact email: E.ingham@leeds.ac.uk Last Modified: 21 Aug 2024 14:48

Files

Documentation

Key to sample/group numbers [342B] Key to sample/group numbers [342B] Key to sample/group numbers [342B] Security: Anyone File name: Sample_group_and_number_key.txt Content type: Documentation Description: Key listing the sterilisation groups for different sample numbers Mime-Type: text/plain License: Creative Commons Attribution 4.0 International (CC BY 4.0) File size: 342B

Data

Collagen and Denatured collagen content [144kB] Collagen and Denatured collagen content [144kB] Collagen and Denatured collagen content [144kB] Security: Anyone File name: sSFT_HYP_DNC_all_data.xlsx Content type: Data Description: Details of the tissue weights and solution volumes used in collagen and denatured collagen assays. Includes calculation of hydroxyproline content. Mime-Type: application/vnd.openxmlformats-officedocument.spreadsheetml.sheet License: Creative Commons Attribution 4.0 International (CC BY 4.0) File size: 144kB

Collagen and Denatured collagen content - raw data [16kB] Collagen and Denatured collagen content - raw data [16kB] Collagen and Denatured collagen content - raw data [16kB] Security: Anyone File name: HYP_DNC_raw_data_files.zip Content type: Data Description: Raw data from spectophotometer for collagen and denatured collagen quantification as .txt files, including a description of the samples containted in each dataset Mime-Type: application/zip License: Creative Commons Attribution 4.0 International (CC BY 4.0) File size: 16kB

Transition temperatures comparison [365B] Transition temperatures comparison [365B] Transition temperatures comparison [365B] Security: Anyone File name: DSC_DSF_Comparison.txt Content type: Data Description: Comparison of differential scanning calorimetry and differential scanning fluorimetry transition temperatures for sterilised superflexor tendon Mime-Type: text/plain License: Creative Commons Attribution 4.0 International (CC BY 4.0) File size: 365B

Transition temperatures comparison - DSC [636B] Transition temperatures comparison - DSC [636B] Transition temperatures comparison - DSC [636B] Security: Anyone File name: sSFT_DSF_Data.txt Content type: Data Description: Thermal transition temperatures of sterilised acellular porcine superflexor tendon (ankle region) as measured by differential scanning caloimetry Mime-Type: text/plain License: Creative Commons Attribution 4.0 International (CC BY 4.0) File size: 636B

Biomechanical testing [19kB] Biomechanical testing [19kB] Biomechanical testing [19kB] Security: Anyone File name: Mechanical_failure_data.xlsx Content type: Data Description: Vaules of Ultimate Tensile Strength, Failure Strain and Young's Modulus for acellular porcine superflexor tendons following irradiation Mime-Type: application/vnd.openxmlformats-officedocument.spreadsheetml.sheet License: Creative Commons Attribution 4.0 International (CC BY 4.0) File size: 19kB

Histological data [13kB] Histological data [13kB] Histological data [13kB] Security: Anyone File name: Microscopy_observation_summary.docx Content type: Data Description: Summary of the observations made across all tendon groups Mime-Type: application/vnd.openxmlformats-officedocument.wordprocessingml.document License: Creative Commons Attribution 4.0 International (CC BY 4.0) File size: 13kB

Histological images [686MB] Histological images [686MB] Histological images [686MB] Security: Anyone File name: Histology_by_sterilisation_treatment.zip Content type: Data Description: Example images from each sample group and each timepoint. Note: more slides were viewed than were captured as histological images. Observations were recorderd ina lab book and are summarised in the Microscopy_observation_summary.docx document. Mime-Type: application/zip License: Creative Commons Attribution 4.0 International (CC BY 4.0) File size: 686MB

Cytotoxicity testing [14kB] Cytotoxicity testing [14kB] Cytotoxicity testing [14kB] Security: Anyone File name: Cytoxicity_observations.xlsx Content type: Data Description: Observations from contact cytotoxicity testing of all tendons Mime-Type: application/vnd.openxmlformats-officedocument.spreadsheetml.sheet License: Creative Commons Attribution 4.0 International (CC BY 4.0) File size: 14kB

Cytotoxicity testing - images [721MB] Cytotoxicity testing - images [721MB] Cytotoxicity testing - images [721MB] Security: Anyone File name: Biocompatibility.zip Content type: Data Description: Representative images of cyotoxicity testing Mime-Type: application/zip License: Creative Commons Attribution 4.0 International (CC BY 4.0) File size: 721MB