Research Data Leeds Repository

Fenn, Katherine and Horne, Jim E. and Crossley, Joel A. and Calabrese, Antonio N. and Radford, Sheena E. and Ranson, Neil A. (2024) Data for 'Outer membrane protein assembly mediated by BAM-SurA complexes'. University of Leeds. [Dataset] https://doi.org/10.5518/1460

Chau, Chalmers C. and Maffeo, Christopher M. and Aksimentiev, Aleksei and Radford, Sheena E. and Hewitt, Eric W. and Actis, Paolo (2024) Data for Single molecule delivery into living cells. University of Leeds. [Dataset] https://doi.org/10.5518/1512

Willis, Leon F. and Trayton, Isabelle and Saunders, Janet C. and Bruque, Maria G. and Birch, William Davis and Westhead, David R. and Day, Katie and Devine, Paul W. A. and Lloyd, Christopher and Kapur, Nikil and Radford, Sheena E. and Darton, Nicholas J. and Brockwell, David J. (2024) Rationalising mAb candidate screening using a single holistic developability parameter' - data. American Chemical Society. [Dataset] https://doi.org/10.5518/1470

Dewison, Katherine and Radford, Sheena E. (2024) Residues 2 to 7 of α-synuclein regulate amyloid formation via lipid-dependent and lipid-independent pathways. University of Leeds. [Dataset] https://doi.org/10.5518/1422

Crossley, Joel A. and Allen, William J. and Watkins, Daniel W. and Sabir, Tara and Radford, Sheena E. and Tuma, Roman and Collinson, Ian and Fessl, Tomas (2023) Dynamic coupling of fast channel gating with slow ATP-turnover underpins protein transport through the Sec-translocon. University of Leeds. [Dataset] https://doi.org/10.5518/1410

Aubrey, Liam D. and Ulamec, Sabine M. and Ninkina, Natalia and Abramycheva, Natalia Y. and Limorenko, Galina and Vasili, Eftychia and Devine, Oliver M. and Wilkinson, Martin and Walko, Martin and Outeiro, Tiago F. and Chaprov, Kirill D. and Muwanga, Sarah and Amadio, Leonardo and Peters, Owen M. and Illarioshkin, Sergey N. and Ranson, Neil A. and Brockwell, David J. and Buchman, Vladimir L. and Radford, Sheena E. (2023) Substitution of Met-38 to Ile in gamma-synuclein found in two patients with amyotrophic lateral sclerosis induces aggregation into amyloid. University of Leeds. [Dataset] https://doi.org/10.5518/1315

Marcuccio, Fabio and Soulias, Dimitrios and Chau, Chalmers C. and Radford, Sheena E. and Hewitt, Eric W. and Actis, Paolo and Edwards, Martin A. (2022) Data for "Mechanistic Study of the Conductance and Enhanced Single-Molecule Detection in a Polymer Electrolyte Nanopore". University of Leeds. [Dataset] https://doi.org/10.5518/1274

Chau, Chalmers C. and Marcuccio, Fabio and Soulias, Dimitrios and Edwards, Martin A. and Tuplin, Andrew and Radford, Sheena E. and Hewitt, Eric W. and Actis, Paolo (2022) Data set for Probing RNA conformations using a polymer electrolyte solid-state nanopore. University of Leeds. [Dataset] https://doi.org/10.5518/1251

Guthertz, Nicolas and Van der Kant, Rob and Smith, Hugh and Maya-Martinez, Roberto and Xu, Yong and Trinh, Chi H. and Iorga, Bogdan I. and Rousseau, Frederic and Schymkowitz, Joost and Brockwell, David J. and Radford, Sheena E. (2022) Dataset associated with 'The effect of mutation on an aggregation-prone protein: An in vivo, in vitro and in silico analysis'. University of Leeds. [Dataset] https://doi.org/10.5518/1073

Maya-Martinez, Roberto and Xu, Yong and Guthertz, Nicolas and Walko, Martin and Sobott, Frank and Karamanos, Theodoros and Breeze, Alexander L. and Radford, Sheena E. (2022) Dimers of D76N-β2-microglobulin display potent anti-amyloid aggregation activity. University of Leeds. [Dataset] https://doi.org/10.5518/1159

Xu, Yong and Maya-Martinez, Roberto and Guthertz, Nicolas and Heath, George R. and Manfield, Iain W. and Breeze, Alexander L. and Sobott, Frank and Foster, Richard and Radford, Sheena E. (2022) Supporting data for "Tuning the rate of aggregation of hIAPP into amyloid using small-molecule modulators of assembly". University of Leeds. [Dataset] https://doi.org/10.5518/1000

White, Paul and Haysom, Samuel and Iadanza, Matthew G. and Higgins, Anna J. and Machin, Jonathan and Whitehouse, James and Carpenter-Platt, Charlotte and Horne, Jim E. and Brockwell, David J. and Ranson, Neil A. and Radford, Sheena E. (2021) Supporting data for “The role of membrane destabilisation and protein dynamics in BAM catalysed OMP folding”. University of Leeds. [Dataset] https://doi.org/10.5518/835

Ulamec, Sabine M. and Radford, Sheena E. (2020) Data associated with 'Looking beyond the core: The role of flanking regions in the aggregation of amyloidogenic peptides and proteins'. University of Leeds. [Dataset] https://doi.org/10.5518/893

Chau, Chalmers C. and Radford, Sheena E. and Hewitt, Eric W. and Actis, Paolo (2020) Dataset for Macromolecular crowding enhances the detection of DNA and proteins by a solid-state nanopore. University of Leeds. [Dataset] https://doi.org/10.5518/841

Calabrese, Antonio N. and Schiffrin, Bob and Watson, Matthew and Walko, Martin and Humes, Julia R. and Karamanos, Theodoros and Horne, Jim E. and White, Paul and Kalli, Antreas and Tuma, Roman and Ashcroft, Alison E. and Brockwell, David J. and Radford, Sheena E. (2020) Inter-domain dynamics in the chaperone SurA and multi-site binding to its outer membrane protein clients - dataset. University of Leeds. [Dataset] https://doi.org/10.5518/701

Doherty, Ciaran P. A. and Ulamec, Sabine M. and Maya-Martinez, Roberto and Good, Sarah C. and Makepeace, Jemma and Khan, G. Nasir and van Oosten-Hawle, Patricija and Radford, Sheena E. and Brockwell, David J. (2019) Data associated with 'A short motif in the N-terminal region of alpha-synuclein plays a critical role in aggregation and function'. University of Leeds. [Dataset] https://doi.org/10.5518/707

Ebo, Jessica S. and Saunders, Janet C. and Devine, Paul W. A. and Gordon, Alice M. and Warwick, Amy S. and Schiffrin, Bob and Chin, Stacey E. and England, Elizabeth and Button, James D. and Lloyd, Christopher and Bond, Nicholas J. and Ashcroft, Alison E. and Radford, Sheena E. and Lowe, David and Brockwell, David J., AstraZeneca (2019) Data associated with 'An in vivo platform to select and evolve aggregation-resistant proteins'. University of Leeds. [Dataset] https://doi.org/10.5518/739

Karamanos, Theodoros and Jackson, Matthew P. and Calabrese, Antonio N. and Goodchild, Sophia C. and Cawood, Emma and Thompson, Gary S. and Kalverda, Arnout P. and Hewitt, Eric W. and Radford, Sheena E. (2019) Structural mapping of oligomeric intermediates in an amyloid assembly pathway - dataset. University of Leeds. [Dataset] https://doi.org/10.5518/329

Martin, Esther M. and Jackson, Matthew P. and Gamerdinger, Martin and Gense, Karina and Karamanos, Theodoros and Humes, Julia R. and Deuerling, Elke and Ashcroft, Alison E. and Radford, Sheena E. (2018) Data associated with 'Conformational flexibility within the nascent polypeptide–associated complex enables its interactions with structurally diverse client proteins'. University of Leeds. [Dataset] https://doi.org/10.5518/295

Dobson, John and Kumar, Amit and Willis, Leon and Higazi, Daniel and Turner, Richard and Lowe, David and Tuma, Roman and Ashcroft, Alison E. and Radford, Sheena E. and Kapur, Nikil and Brockwell, David J., MedImmune (2017) Data associated with 'Inducing protein aggregation by extensional flow'. University of Leeds. [Dataset] https://doi.org/10.5518/125