Research Data Leeds Repository

McKay, Conor E., Deans, Miles, Connor, Jack P., Saunders, Janet C., Lloyd, Christopher, Radford, Sheena E. and Brockwell, David J. (2025) Data associated with "Employing Deep Mutational Scanning in the E. coli Periplasm to Decode the Thermodynamic Landscape For Amyloid Formation". University of Leeds. [Dataset] https://doi.org/10.5518/1653

Connor, Jack P., Radford, Sheena E. and Brockwell, David J. (2025) Data for 'Structural and Thermodynamic Classification of Amyloid Polymorphs'. University of Leeds. [Dataset] https://doi.org/10.5518/1659

Hughes, Matt D. G., Cook, Kalila, Cussons, Sophie, Boroumand, Ahmad, Tyler, Arwen I. I., Head, David, Brockwell, David J. and Dougan, Lorna (2024) Capturing Dynamic Assembly of Nanoscale Proteins During Network Formation. University of Leeds. [Dataset] https://doi.org/10.5518/1587

Hughes, Matt D. G., Cussons, Sophie, Borumand, Ahmad, Tyler, Arwen I. I., Brockwell, David J. and Dougan, Lorna (2024) Capturing the Impact of Protein Unfolding on the Dynamic Assembly of Protein Networks. [Dataset]. University of Leeds. [Dataset] https://doi.org/10.5518/1632

Hughes, Matt D. G., West, Daniel, Wurr, Rebecca, Cussons, Sophie, Cook, Kalila, Mahmoudi, Najet, Head, David, Brockwell, David J. and Dougan, Lorna (2024) Competition between cross-linking and force-induced local conformational changes determines the structure and mechanics of labile protein networks. University of Leeds. [Dataset] https://doi.org/10.5518/1582

Laurent, Harrison, Brockwell, David J. and Dougan, Lorna (2024) Nanomachine Networks: Functional All-Enzyme Hydrogels from Photochemical Cross-Linking of Glucose Oxidase - Dataset. University of Leeds. [Dataset] https://doi.org/10.5518/1590

Willis, Leon F., Trayton, Isabelle, Saunders, Janet C., Bruque, Maria G., Birch, William Davis, Westhead, David R., Day, Katie, Devine, Paul W. A., Lloyd, Christopher, Kapur, Nikil, Radford, Sheena E., Darton, Nicholas J. and Brockwell, David J. (2024) Rationalising mAb candidate screening using a single holistic developability parameter' - data. American Chemical Society. [Dataset] https://doi.org/10.5518/1470

Hughes, Matt D. G., Cussons, Sophie, Hanson, Benjamin S., Cook, Kalila, Feller, Tímea, Mahmoudi, Najet, Baker, Daniel, Ariëns, Robert, Head, David, Brockwell, David J. and Dougan, Lorna (2023) Building block aspect ratio controls assembly, architecture, and mechanics of synthetic and natural protein networks - dataset. University of Leeds. [Dataset] https://doi.org/10.5518/1344

Brown, Christa P., Hughes, Matt D. G., Mahmoudi, Najet, Brockwell, David J., Coletta, P. Louise, Peyman, Sally A., Evans, Stephen D. and Dougan, Lorna (2023) Encapsulation of Microbubbles within Folded Protein Hydrogels: Effects on the mechanical and structural properties. University of Leeds. [Dataset] https://doi.org/10.5518/1212

Aubrey, Liam D., Ulamec, Sabine M., Ninkina, Natalia, Abramycheva, Natalia Y., Limorenko, Galina, Vasili, Eftychia, Devine, Oliver M., Wilkinson, Martin, Walko, Martin, Outeiro, Tiago F., Chaprov, Kirill D., Muwanga, Sarah, Amadio, Leonardo, Peters, Owen M., Illarioshkin, Sergey N., Ranson, Neil A., Brockwell, David J., Buchman, Vladimir L. and Radford, Sheena E. (2023) Substitution of Met-38 to Ile in gamma-synuclein found in two patients with amyotrophic lateral sclerosis induces aggregation into amyloid. University of Leeds. [Dataset] https://doi.org/10.5518/1315

Guthertz, Nicolas, Van der Kant, Rob, Smith, Hugh, Maya-Martinez, Roberto, Xu, Yong, Trinh, Chi H., Iorga, Bogdan I., Rousseau, Frederic, Schymkowitz, Joost, Brockwell, David J. and Radford, Sheena E. (2022) Dataset associated with 'The effect of mutation on an aggregation-prone protein: An in vivo, in vitro and in silico analysis'. University of Leeds. [Dataset] https://doi.org/10.5518/1073

Hughes, Matt D. G., Cussons, Sophie, Mahmoudi, Najet and Brockwell, David J. (2022) Tuning Protein Hydrogel Mechanics through Modulation of Nanoscale Unfolding and Entanglement in Postgelation Relaxation. University of Leeds. [Dataset] https://doi.org/10.5518/1174

White, Paul, Haysom, Samuel, Iadanza, Matthew G., Higgins, Anna J., Machin, Jonathan, Whitehouse, James, Carpenter-Platt, Charlotte, Horne, Jim E., Brockwell, David J., Ranson, Neil A. and Radford, Sheena E. (2021) Supporting data for “The role of membrane destabilisation and protein dynamics in BAM catalysed OMP folding”. University of Leeds. [Dataset] https://doi.org/10.5518/835

Calabrese, Antonio N., Schiffrin, Bob, Watson, Matthew, Walko, Martin, Humes, Julia R., Karamanos, Theodoros, Horne, Jim E., White, Paul, Kalli, Antreas, Tuma, Roman, Ashcroft, Alison E., Brockwell, David J. and Radford, Sheena E. (2020) Inter-domain dynamics in the chaperone SurA and multi-site binding to its outer membrane protein clients - dataset. University of Leeds. [Dataset] https://doi.org/10.5518/701

Hughes, Matt D. G., Cussons, Sophie, Mahmoudi, Najet, Brockwell, David J. and Dougan, Lorna (2020) Single Molecule Protein Stabilisation Translates to Macromolecular Mechanics of Protein Network - Dataset. University of Leeds. [Dataset] https://doi.org/10.5518/799

Doherty, Ciaran P. A., Ulamec, Sabine M., Maya-Martinez, Roberto, Good, Sarah C., Makepeace, Jemma, Khan, G. Nasir, van Oosten-Hawle, Patricija, Radford, Sheena E. and Brockwell, David J. (2019) Data associated with 'A short motif in the N-terminal region of alpha-synuclein plays a critical role in aggregation and function'. University of Leeds. [Dataset] https://doi.org/10.5518/707

Ebo, Jessica S., Saunders, Janet C., Devine, Paul W. A., Gordon, Alice M., Warwick, Amy S., Schiffrin, Bob, Chin, Stacey E., England, Elizabeth, Button, James D., Lloyd, Christopher, Bond, Nicholas J., Ashcroft, Alison E., Radford, Sheena E., Lowe, David and Brockwell, David J., AstraZeneca (2019) Data associated with 'An in vivo platform to select and evolve aggregation-resistant proteins'. University of Leeds. [Dataset] https://doi.org/10.5518/739

Dobson, John, Kumar, Amit, Willis, Leon, Higazi, Daniel, Turner, Richard, Lowe, David, Tuma, Roman, Ashcroft, Alison E., Radford, Sheena E., Kapur, Nikil and Brockwell, David J., MedImmune (2017) Data associated with 'Inducing protein aggregation by extensional flow'. University of Leeds. [Dataset] https://doi.org/10.5518/125