Research Data Leeds Repository

Encapsulation of Microbubbles within Folded Protein Hydrogels: Effects on the mechanical and structural properties

Brown, Christa P. and Hughes, Matt D. G. and Mahmoudi, Najet and Brockwell, David J. and Coletta, Louise and Peyman, Sally A. and Evans, Stephen D. and Dougan, Lorna (2023) Encapsulation of Microbubbles within Folded Protein Hydrogels: Effects on the mechanical and structural properties. University of Leeds. [Dataset] https://doi.org/10.5518/1212

Dataset description

The data covers a study of folded protein hydrogel with embedded microbubbles, and their examination using rheology, small angle scattering and microscopy.

Keywords:	Protein, mechanics, hydrogels, biomaterials, structure, microbubbles, SANS, rheology
Subjects:	C000 - Biological sciences > C100 - Biology C000 - Biological sciences > C700 - Molecular biology, biophysics & biochemistry F000 - Physical sciences > F100 - Chemistry F000 - Physical sciences > F300 - Physics
Divisions:	Faculty of Engineering and Physical Sciences > School of Physics and Astronomy
Related resources:	Location Type https://doi.org/10.1039/d2bm01918c Publication
License:	Creative Commons Attribution 4.0 International (CC BY 4.0)
Date deposited:	22 Feb 2023 10:49
URI:	http://archive.researchdata.leeds.ac.uk/id/eprint/1074
Additional details Additional details Creators: Creators ORCID Other ID Email Primary affiliation Primary affiliation ID Primary affiliation ID type Secondary affiliation Secondary affiliation ID Secondary affiliation ID type Brown, Christa P. https://orcid.org/0000-0002-6551-3953 University of Leeds https://ror.org/024mrxd33 ror Hughes, Matt D. G. https://orcid.org/0000-0001-5838-7939 University of Leeds https://ror.org/024mrxd33 ror Mahmoudi, Najet https://orcid.org/0000-0003-4936-6911 University of Leeds https://ror.org/024mrxd33 ror Brockwell, David J. https://orcid.org/0000-0002-0802-5937 University of Leeds https://ror.org/024mrxd33 ror Coletta, Louise https://orcid.org/0000-0002-3858-6073 University of Leeds https://ror.org/024mrxd33 ror Peyman, Sally A. https://orcid.org/0000-0002-1600-5100 University of Leeds https://ror.org/024mrxd33 ror Evans, Stephen D. https://orcid.org/0000-0001-8342-5335 University of Leeds https://ror.org/024mrxd33 ror Dougan, Lorna https://orcid.org/0000-0002-2620-5827 University of Leeds https://ror.org/024mrxd33 ror Type of data: Dataset Research funders: Alumni Leeds,Margaret Steel Award, NIHR, EPSRC Grant numbers: n/a, EPP023266/1, EP/S001069/1, EP/W033151/1, EP/P02288X/1 Publication date: 2023 Resource language: English Publisher: University of Leeds Contact Email Address: py14cpb@leeds.ac.uk Last Modified: 26 Jan 2024 13:14

Files

Data

Circular Dichroism [64kB] Circular Dichroism [64kB] Circular Dichroism [64kB] Visible to: Anyone File name: circular_dichroism.zip Content type: Data Description: circular dichroism data for pre and post gelation of BSA hydrogels, in the absence and presence of microbubbles Mime-Type: application/zip License: Creative Commons Attribution 4.0 International (CC BY 4.0) File size: 64kB

MB concentration in solution and in BSA hydrogel [4GB] MB concentration in solution and in BSA hydrogel [4GB] MB concentration in solution and in BSA hydrogel [4GB] Visible to: Anyone File name: microbubble_concentrations.zip Content type: Data Mime-Type: application/zip License: Creative Commons Attribution 4.0 International (CC BY 4.0) File size: 4GB

Ultrasound on microbubbles in BSA hydrogel [7MB] Ultrasound on microbubbles in BSA hydrogel [7MB] Ultrasound on microbubbles in BSA hydrogel [7MB] Visible to: Anyone File name: Ultrasound_bursting_microbubbles.zip Content type: Data Description: Images of the BSA hydrogel before and after ultrasound Mime-Type: application/zip License: Creative Commons Attribution 4.0 International (CC BY 4.0) File size: 7MB

cross-linking quantification [44kB] cross-linking quantification [44kB] cross-linking quantification [44kB] Visible to: Anyone File name: dityrosine_emission.xlsx Content type: Data Description: Data of the dityrosine emission from BSA hydrogels, comparing ithe emission in the abscence and presence of microbubbles Mime-Type: application/vnd.openxmlformats-officedocument.spreadsheetml.sheet License: Creative Commons Attribution 4.0 International (CC BY 4.0) File size: 44kB

microbubble trajectories [43kB] microbubble trajectories [43kB] microbubble trajectories [43kB] Visible to: Anyone File name: microbubble_trajectories.xlsx Content type: Data Description: trajectories of the movement of microbubbles through BSA hydrogel compared to buffer solution Mime-Type: application/vnd.openxmlformats-officedocument.spreadsheetml.sheet License: Creative Commons Attribution 4.0 International (CC BY 4.0) File size: 43kB

Rheological characterisation [3MB] Rheological characterisation [3MB] Rheological characterisation [3MB] Visible to: Anyone File name: rheology.xlsx Content type: Data Description: TimeSweep data for the gelation curves, frequency sweep, stress-strain curves and non-linear behaviour Mime-Type: application/vnd.openxmlformats-officedocument.spreadsheetml.sheet License: Creative Commons Attribution 4.0 International (CC BY 4.0) File size: 3MB