Research Data Leeds Repository

Rationalising mAb candidate screening using a single holistic developability parameter' - data

Citation

Willis, Leon F. and Trayton, Isabelle and Saunders, Janet C. and Bruque, Maria G. and Birch, William Davis and Westhead, David R. and Day, Katie and Devine, Paul W. A. and Lloyd, Christopher and Kapur, Nikil and Radford, Sheena E. and Darton, Nicholas J. and Brockwell, David J. (2024) Rationalising mAb candidate screening using a single holistic developability parameter' - data. American Chemical Society. [Dataset] https://doi.org/10.5518/1470¹

Dataset description

Raw and Ranked data from 'Rationalising mAb candidate screening using a single holistic developability parameter'

Subjects:	C000 - Biological sciences > C700 - Molecular biology, biophysics & biochemistry2 G000 - Mathematical sciences > G300 - Statistics > G310 - Applied statistics3
Divisions:	Faculty of Biological Sciences > Astbury Centre for Structural Molecular Biology4 Faculty of Biological Sciences > School of Molecular and Cellular Biology5 Faculty of Engineering and Physical Sciences > School of Mechanical Engineering6
Related resources:	Location Type https://doi.org/10.1021/acs.molpharmaceut.4c008297 Publication https://eprints.whiterose.ac.uk/220534/8 Publication
License:	Creative Commons Attribution 4.0 International (CC BY 4.0)
Date deposited:	17 Dec 2024 15:41
URI:	https://archive.researchdata.leeds.ac.uk/id/eprint/13549
Additional details Additional details Creators or authors: Creators ORCID Other ID Email Primary affiliation Primary affiliation ID Primary affiliation ID type Secondary affiliation Secondary affiliation ID Secondary affiliation ID type Willis, Leon F. https://orcid.org/0000-0001-6616-371610 University of Leeds https://ror.org/024mrxd33 ror Trayton, Isabelle AstraZeneca PLC https://ror.org/04r9x1a08 ror Saunders, Janet C. AstraZeneca PLC https://ror.org/04r9x1a08 ror Immunocore Holdings PLC https://ror.org/014xzez86 ror Bruque, Maria G. AstraZeneca PLC https://ror.org/04r9x1a08 ror University of Birmingham https://ror.org/03angcq70 ror Birch, William Davis https://orcid.org/0000-0002-3352-172111 University of Leeds https://ror.org/024mrxd33 ror Westhead, David R. https://orcid.org/0000-0002-0519-382012 University of Leeds https://ror.org/024mrxd33 ror Day, Katie AstraZeneca PLC https://ror.org/04r9x1a08 ror Devine, Paul W. A. AstraZeneca PLC https://ror.org/04r9x1a08 ror Lloyd, Christopher AstraZeneca PLC https://ror.org/04r9x1a08 ror Kapur, Nikil https://orcid.org/0000-0003-1041-839013 University of Leeds https://ror.org/024mrxd33 ror Radford, Sheena E. https://orcid.org/0000-0002-3079-803914 University of Leeds https://ror.org/024mrxd33 ror Darton, Nicholas J. AstraZeneca PLC https://ror.org/04r9x1a08 ror Brockwell, David J. https://orcid.org/0000-0002-0802-593715 University of Leeds https://ror.org/024mrxd33 ror Type of data: Dataset Research funders: EPSRC, AstraZeneca PLC, Royal Academy of Engineering, The Royal Society Grant numbers: EP/IO3327/1, RSRP\R1\211057 Publication date: 2024 Resource language: English Metadata language: English Publisher: American Chemical Society Contact email: l.f.willis@leeds.ac.uk16 Last Modified: 24 Jan 2025 12:38

Files

Documentation

README_Willis_2024.txt [4kB] 17 README_Willis_2024.txt [4kB] 18 README_Willis_2024.txt [4kB] 19 Security: Anyone File name: README_Willis_2024.txt20 Content type: Documentation Mime-Type: text/plain License: Creative Commons Attribution 4.0 International (CC BY 4.0) File size: 4kB

Data

Table of data [28kB] 21 Table of data [28kB] 22 Table of data [28kB] 23 Security: Anyone File name: raw_and_ranked_data_Rationalising_mAb_candidate_screening_using_a_single_holistic_developability_parameter.xlsx24 Content type: Data Description: The Excel file contains all of the processed raw data, in addition to the Spearman's ranked data from our publication. Variables are colour coded according to the Tables and Figures in the paper Mime-Type: application/vnd.openxmlformats-officedocument.spreadsheetml.sheet License: Creative Commons Attribution 4.0 International (CC BY 4.0) File size: 28kB

• 1. https://doi.org/10.5518/1470
• 2. https://archive.researchdata.leeds.ac.uk/view/subjects/C700.html
• 3. https://archive.researchdata.leeds.ac.uk/view/subjects/G310.html
• 4. https://archive.researchdata.leeds.ac.uk/view/divisions/ACSMB/
• 5. https://archive.researchdata.leeds.ac.uk/view/divisions/SMCB/
• 6. https://archive.researchdata.leeds.ac.uk/view/divisions/SME/
• 7. https://doi.org/10.1021/acs.molpharmaceut.4c00829
• 8. https://eprints.whiterose.ac.uk/220534/
• 9. https://archive.researchdata.leeds.ac.uk/id/eprint/1354
• 10. https://orcid.org/0000-0001-6616-3716
• 11. https://orcid.org/0000-0002-3352-1721
• 12. https://orcid.org/0000-0002-0519-3820
• 13. https://orcid.org/0000-0003-1041-8390
• 14. https://orcid.org/0000-0002-3079-8039
• 15. https://orcid.org/0000-0002-0802-5937
• 16. mailto:l.f.willis@leeds.ac.uk
• 17. https://archive.researchdata.leeds.ac.uk/1354/2/README_Willis_2024.txt
• 18. https://archive.researchdata.leeds.ac.uk/1354/2/README_Willis_2024.txt
• 19. https://archive.researchdata.leeds.ac.uk/1354/2/README_Willis_2024.txt
• 20. https://archive.researchdata.leeds.ac.uk/1354/2/README_Willis_2024.txt
• 21. https://archive.researchdata.leeds.ac.uk/1354/1/raw_and_ranked_data_Rationalising_mAb_candidate_screening_using_a_single_holistic_developability_parameter.xlsx
• 22. https://archive.researchdata.leeds.ac.uk/1354/1/raw_and_ranked_data_Rationalising_mAb_candidate_screening_using_a_single_holistic_developability_parameter.xlsx
• 23. https://archive.researchdata.leeds.ac.uk/1354/1/raw_and_ranked_data_Rationalising_mAb_candidate_screening_using_a_single_holistic_developability_parameter.xlsx
• 24. https://archive.researchdata.leeds.ac.uk/1354/1/raw_and_ranked_data_Rationalising_mAb_candidate_screening_using_a_single_holistic_developability_parameter.xlsx