Research Data Leeds Repository

Citation

Au, Cheuk Wang and Ross, James (2024) Computational and Experimental Data on Surface Mutations to Cholera Toxin B-subunit. University of Leeds. [Dataset] https://doi.org/10.5518/1479

Dataset description

This dataset includes data records for raw and/or processed data associated with the publication below. These include datafiles from computational assessments of the stability and interaction energy for Cholera toxin B-subunit and it's association with its ligand GM1. This dataset also includes experimental data from Differential Scanning Calorimetry and Isothermal Titration Calorimetry, as well as raw gels from protein expression and purification.

Subjects:	B000 - Subjects allied to medicine > B200 - Pharmacology, toxicology & pharmacy > B220 - Toxicology C000 - Biological sciences > C700 - Molecular biology, biophysics & biochemistry
Divisions:	Faculty of Biological Sciences > School of Molecular and Cellular Biology
Related resources:	Location Type https://doi.org/10.3390/toxins16030133 Publication https://eprints.whiterose.ac.uk/209910/ Publication
License:	Creative Commons Attribution 4.0 International (CC BY 4.0)
Date deposited:	12 Mar 2024 09:11
URI:	https://archive.researchdata.leeds.ac.uk/id/eprint/1256
Additional details Additional details Creators or authors: Creators ORCID Other ID Email Primary affiliation Primary affiliation ID Primary affiliation ID type Secondary affiliation Secondary affiliation ID Secondary affiliation ID type Au, Cheuk Wang https://orcid.org/0009-0007-0781-820X University of Leeds https://ror.org/024mrxd33 ror Ross, James https://orcid.org/0000-0002-4784-103X University of Leeds https://ror.org/024mrxd33 ror Type of data: Dataset Research funders: EPSRC Grant numbers: EP/W022842/1 Publication date: 2024 Resource language: English Metadata language: English Publisher: University of Leeds Contact email: j.f.ross@leeds.ac.uk Last Modified: 15 Dec 2025 15:09

Files

Documentation

readme.txt [3kB] readme.txt [3kB] readme.txt [3kB] Security: Anyone File name: readme.txt Content type: Documentation Mime-Type: text/plain License: Creative Commons Attribution 4.0 International (CC BY 4.0) File size: 3kB

Data

CTB-sequences.zip [67kB] CTB-sequences.zip [67kB] CTB-sequences.zip [67kB] Security: Anyone File name: CTB-sequences.zip Content type: Data Mime-Type: application/zip License: Creative Commons Attribution 4.0 International (CC BY 4.0) File size: 67kB

DSF.zip [6MB] DSF.zip [6MB] DSF.zip [6MB] Security: Anyone File name: DSF.zip Content type: Data Mime-Type: application/zip License: Creative Commons Attribution 4.0 International (CC BY 4.0) File size: 6MB

ITC.zip [202kB] ITC.zip [202kB] ITC.zip [202kB] Security: Anyone File name: ITC.zip Content type: Data Mime-Type: application/zip License: Creative Commons Attribution 4.0 International (CC BY 4.0) File size: 202kB

Rosetta.zip [1MB] Rosetta.zip [1MB] Rosetta.zip [1MB] Security: Anyone File name: Rosetta.zip Content type: Data Mime-Type: application/zip License: Creative Commons Attribution 4.0 International (CC BY 4.0) File size: 1MB

SI-Gels.png [2MB] SI-Gels.png [2MB] SI-Gels.png [2MB] Security: Anyone File name: SI-Gels.png Content type: Data Mime-Type: image/png License: Creative Commons Attribution 4.0 International (CC BY 4.0) File size: 2MB