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Dataset supporting the publication ‘A Comprehensive Combined Experimental and Computational Framework for Pre-clinical Wear Simulation of Total Knee Replacements’
Citation
Abdelgaied, Abdellatif and Fisher, John and Jennings, Louise (2017) Dataset supporting the publication ‘A Comprehensive Combined Experimental and Computational Framework for Pre-clinical Wear Simulation of Total Knee Replacements’. University of Leeds. [Dataset] https://doi.org/10.5518/269
Dataset description
A more robust pre-clinical wear simulation framework is required in order to simulate wider and higher ranges of activities, observed in different patient populations such as younger more active patients. Such a framework will help to understand and address the reported higher failure rates for younger and more active patients (National_Joint_Registry, 2016). The current study has developed and validated a comprehensive combined experimental and computational framework for pre-clinical wear simulation of total knee replacements (TKR). The input mechanical (elastic modulus and Poisson’s ratio) and wear parameters and of the moderately cross-linked ultra-high molecular weight polyethylene (UHMWPE) bearing material were independently measured from experimental studies under realistic test conditions, similar to the loading conditions found in the total knee replacements.. The wear predictions from the computational wear simulation were validated against the direct experimental wear measurements for size 3 Sigma curved total knee replacements (DePuy, UK) in an independent experimental wear simulation study under three different daily activities; walking, deep squat, and stairs ascending kinematic conditions. The measured compressive mechanical properties of the moderately cross-linked UHMWPE material were more than 20% lower than that reported in the literature under tensile test conditions. The pin-on-plate wear coefficient of moderately cross-linked UHMWPE was significantly dependant of the contact stress and the degree of cross-shear at the articulating surfaces. The computational wear predictions for the TKR from the current framework were consistent and in a good agreement with the independent full TKR experimental wear simulation measurements, with 0.94 coefficient of determination of the framework. In addition, the comprehensive combined experimental and computational framework was able to explain the complex experimental wear trends from the three different daily activities investigated. Therefore, such a framework can be adopted as a pre-clinical simulation approach to optimise different designs, materials, as well as patient’s specific total knee replacements for a range of activities.
Files
Documentation
Read me [2kB]  |
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Read me [2kB] Data
Combined experimental and computational framework for pre-clinical simulation of total knee replacements [61kB]  |
Multidirectional pin-on-plate wear simulator [3MB]  |
Poisson’s ratio and equivalent elastic modulus experimental tests [1MB]  |
Six station electromechanically driven knee simulator (Simulation Solutions, UK), and the controlled axes of articulation for each station [2MB]  |
Axial load (a), anterior posterior displacement (b), flexion extension angle (c), and internal external rotation (d) input profiles for standard walking, deep squat, and stairs ascending kinematics [116kB]  |
Poisson’s ratio and average elastic modulus for moderately cross-linked UHMWPE under compressive test conditions [92kB]  |
Wear coefficients for moderately cross-linked UHMWPE under different cross-shear ratios (mean ± 95% CI, n=6), and 11 MPa contact stress [59kB]  |
Wear coefficients for moderately cross-linked UHMWPE under different applied non-dimensional contact stresses (mean ± 95% CI, n=6), and 0.087 cross-shear ratio [69kB]  |
Experimental (mean ± 95% CI, n=6) and predicted (Eq. 6) wear coefficients for moderately cross-linked UHMWPE under different cross-shear ratios and different contact stresses [186kB]  |
Predicted contact area [mm2], average contact stress [MPa], and percentage contribution to the total wear at different percentage of the loading cycle under standard (a), deep squat (b), and stairs ascending (c) kinematic conditions [127kB]  |
Experimental and computational volumetric wear rates [mm3 /mc] (mean ±95 % CI, n=6) under standard walking, deep squat, and stairs ascending kinematic conditions [93kB]  |
All figures [8MB] |
Pin-on-plate test conditions [13kB] |
The predicted volumetric wear rates, average contact area, contact stress, and CS under standard walking, deep squat, and stairs ascending kinematic conditions [13kB] |
The predicted volumetric wear rates, average contact area, contact stress, and CS under standard walking, deep squat, and stairs ascending kinematic conditions [13kB] |
All tables [31kB] |
Input profiles [20kB] |
Elastic modulus and Poisson's ratio tests [8kB] |
Pin-on-plate wear test results [9kB] |
Full-knee simulation results [25kB] |