Dataset supporting the publication:
Abdelgaied A, Fisher J, Jennings LM. A comprehensive combined experimental and computational framework for pre-clinical wear simulation of total knee replacements. 
Journal of the Mechanical Behavior of Biomedical Materials, 2018;https://doi.org/10.1016/j.jmbbm.2017.11.022.

Figure 1: Combined experimental and computational framework for pre-clinical simulation of total knee replacements.
Figure 2: Multidirectional pin-on-plate wear simulator.
Figure 3: Poisson’s ratio and equivalent elastic modulus experimental tests.
Figure 4: Six station electromechanically driven knee simulator (Simulation Solutions, UK), and the controlled axes of articulation for each station. 
Figure 5: Axial load (a), anterior posterior displacement (b), flexion extension angle (c), and internal external rotation (d) input profiles for standard walking, deep squat, and stairs ascending kinematics. 
Figure 6: Poisson’s ratio and average elastic modulus for moderately cross-linked UHMWPE under compressive test conditions.
Figure 7: Wear coefficients for moderately cross-linked UHMWPE under different cross-shear ratios (mean ± 95% CI, n=6), and 11 MPa contact stress.
Figure 8: Wear coefficients for moderately cross-linked UHMWPE under different applied non-dimensional contact stresses (mean ± 95% CI, n=6), and 0.087 cross-shear ratio.
Figure 9: Experimental (mean ± 95% CI, n=6) and predicted (Eq. 6) wear coefficients for moderately cross-linked UHMWPE under different cross-shear ratios and different contact stresses. 
Figure 10: Predicted contact area [mm2], average contact stress [MPa], and percentage contribution to the total wear at different percentage of the loading cycle under standard (a), deep squat (b), and stairs ascending (c) kinematic conditions. 
Figure 11: Experimental and computational volumetric wear rates [mm3 /mc] (mean ±95 % CI, n=6) under standard walking, deep squat, and stairs ascending kinematic conditions.

Table 1: Pin-on-plate test conditions.
Table 2: The predicted volumetric wear rates, average contact area, contact stress, and CS under standard walking, deep squat, and stairs ascending kinematic conditions.
Table 3: The predicted volumetric wear rates, average contact area, contact stress, and CS under standard walking, deep squat, and stairs ascending kinematic conditions.


Input_profiles.xlsx: Input profiles for standard walking, deep squat, and stairs ascending kinematics.
Mechanical_test.xlsx: Elastic modulus and Poisson's ratio tests
Pin-on-plate_wear_test.xlsx: Pin-on-plate wear test results
Full-knee_simulation_results.xlsx:  Full-knee simulation results