Research Data Leeds Repository

Citation

Chau, Chalmers C.C., Gupta, Varun, Heath, George R., Walti, Christoph and Actis, Paolo (2026) Data for Visualizing and Quantifying microRNA-Induced DNA Origami Separation at the Nanoscale. University of Leeds. [Dataset] https://doi.org/10.5518/1770

Dataset description

Data used for the associated manuscript "Visualizing and Quantifying microRNA-Induced DNA Origami Separation at the Nanoscale". The repository contains 3 types of data, data associated with high-speed AFM, data associated with solid-state nanopore translocation data, and data associated with the DNA origami design. The high-speed AFM data contains video snapshots of the displacement reaction captured and associated raw image file. The nanopore readout data are in abf format, files can be opened through python with pyABF package or pClamp software. The DNA origami design file can be opened with Cadnano (free to use)

Keywords:	Nanopore, DNA origami, High speed AFM
Subjects:	H000 - Engineering > H600 - Electronic & electrical engineering C000 - Biological sciences > C700 - Molecular biology, biophysics & biochemistry
Divisions:	Faculty of Engineering and Physical Sciences > School of Electronic and Electrical Engineering Faculty of Engineering and Physical Sciences > School of Physics and Astronomy
Related resources:	Location Type https://doi.org/10.1002/anie.6443787 Publication
License:	Creative Commons Attribution 4.0 International (CC BY 4.0)
Date deposited:	18 Mar 2026 21:06
URI:	https://archive.researchdata.leeds.ac.uk/id/eprint/1533
Additional details Additional details Creators or authors: Creators ORCID Other ID Email Primary affiliation Primary affiliation ID Primary affiliation ID type Secondary affiliation Secondary affiliation ID Secondary affiliation ID type Chau, Chalmers C.C. https://orcid.org/0000-0002-3134-6798 University of Leeds https://ror.org/024mrxd33 ror Gupta, Varun https://orcid.org/0009-0006-8588-9057 University of Leeds https://ror.org/024mrxd34 ror Heath, George R. https://orcid.org/0000-0001-6431-2191 University of Leeds https://ror.org/024mrxd35 ror Walti, Christoph https://orcid.org/0000-0001-9286-5359 University of Leeds https://ror.org/024mrxd36 ror Actis, Paolo https://orcid.org/0000-0002-7146-1854 University of Leeds https://ror.org/024mrxd37 ror Type of data: Dataset Research funders: Engineering and Physical Sciences Research Council, Engineering and Physical Sciences Research Council, Biotechnology and Biological Sciences Research Council Grant numbers: EP/W004933/1, EP/W034735/1, BB/X003086/1 Publication date: 2026 Resource language: English Metadata language: English Publisher: University of Leeds Contact email: c.c.chau@leeds.ac.uk Last Modified: 19 Mar 2026 16:43

Files

Documentation

Readme [6kB] Readme [6kB] Readme [6kB] Security: Anyone File name: README_Chau_2026.txt Content type: Documentation Mime-Type: text/plain License: Creative Commons Attribution 4.0 International (CC BY 4.0) File size: 6kB

Data

High-speed AFM movies [3GB] High-speed AFM movies [3GB] High-speed AFM movies [3GB] Security: Anyone File name: high-speed_AFM_data.zip Content type: Data Description: High-speed AFM data and statistic Mime-Type: application/zip License: Creative Commons Attribution 4.0 International (CC BY 4.0) File size: 3GB

DNA Origami design data [170kB] DNA Origami design data [170kB] DNA Origami design data [170kB] Security: Anyone File name: DNA_Origami_design_data.zip Content type: Data Description: Cadnano design and staple list of the DNA origami Mime-Type: application/zip License: Creative Commons Attribution 4.0 International (CC BY 4.0) File size: 170kB

Nanopore data for Figs 2, 5, S5, S6, S15 [1GB] Nanopore data for Figs 2, 5, S5, S6, S15 [1GB] Nanopore data for Figs 2, 5, S5, S6, S15 [1GB] Security: Anyone File name: Nanopore_data.zip Content type: Data Description: Nanopore Translocation data Mime-Type: application/zip License: Creative Commons Attribution 4.0 International (CC BY 4.0) File size: 1GB