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Ire1-LD activation by unfolded protein substrate and molecular chaperone BiP
Citation
Zhuravleva, Anastasia, Hurst, Nicholas, Dawes, Sam and Grey, Gabriel (2024) Ire1-LD activation by unfolded protein substrate and molecular chaperone BiP. University of Leeds. [Dataset] https://doi.org/10.5518/1533
Dataset description
Biophysical characterization of how the molecular chaperone BiP and a model Ire1 substrate interdependently control activation of the ER stress sensor Ire1
| Keywords: | Ire1, Hsp70, UPR | ||||||||
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| Subjects: | C000 - Biological sciences > C700 - Molecular biology, biophysics & biochemistry | ||||||||
| Divisions: | Faculty of Biological Sciences > School of Molecular and Cellular Biology | ||||||||
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| License: | Creative Commons Attribution 4.0 International (CC BY 4.0) | ||||||||
| Date deposited: | 24 Jul 2024 12:36 | ||||||||
| URI: | https://archive.researchdata.leeds.ac.uk/id/eprint/1307 | ||||||||
Files
Documentation
readme [10kB]  |
readme [10kB] 
readme [10kB] Data
Construct details [19kB] |
Data for Supplementary Fig 12 [1MB] |
Data for Supplementary Fig 14 [762kB] |
MST data (Figure 1a) [18kB] |
DLS data (Figure 1b and 2a) [525kB] |
Data for Figure 2b [22kB] |
Data for Figure 2c [18MB]  |
Data for Figure 2d [14MB]  |
Data for Figure 3b [34kB] |
Data for Figure 4c [30kB] |
Data for Supplementary Fig 11b [28kB] |
Consurf Outputs for Supplementary Figure 13 [1MB] |
Data for Supplementary Fig 15b [27kB] |
Data for Supplementary Fig 15c [29kB] |
Data for Supplementary Figure 16 [44kB] |
NMR data for Supplementary Figure 8a [3MB] |
Data for Supplementary Fig 9 [437kB] |
Data for Supplementary Figure 16 [87kB]  |
Data for Supplementary Figure 17b [21kB] |
Data for Supplementary Table 1 [6kB] |
NMR data for Supplementary Figure 11 [63MB] |
Data for Supplementary Figure 4 [45kB] |
Data for Supplementary Figures 6 and 7 [667kB] |