Research Data Leeds Repository

Ire1-LD activation by unfolded protein substrate and molecular chaperone BiP

Citation

Zhuravleva, Anastasia and Hurst, Nicholas and Dawes, Sam and Grey, Gabriel (2024) Ire1-LD activation by unfolded protein substrate and molecular chaperone BiP. University of Leeds. [Dataset] https://doi.org/10.5518/1533

Dataset description

Biophysical characterization of how the molecular chaperone BiP and a model Ire1 substrate interdependently control activation of the ER stress sensor Ire1

Keywords:

Ire1, Hsp70, UPR

Subjects:

C000 - Biological sciences > C700 - Molecular biology, biophysics & biochemistry

Divisions:

Faculty of Biological Sciences > School of Molecular and Cellular Biology

Related resources:

Location	Type
https://doi.org/10.1101/2024.02.16.579620	Publication

License:

Creative Commons Attribution 4.0 International (CC BY 4.0)

Date deposited:

24 Jul 2024 12:36

URI:

https://archive.researchdata.leeds.ac.uk/id/eprint/1307

Additional details

Files

Documentation

readme [10kB]

readme [10kB]

Data

Construct details [19kB]

Data for Supplementary Fig 12 [1MB]

Data for Supplementary Fig 14 [762kB]

MST data (Figure 1a) [18kB]

DLS data (Figure 1b and 2a) [525kB]

Data for Figure 2b [22kB]

Data for Figure 2c [18MB]

Data for Figure 2d [14MB]

Data for Figure 3b [34kB]

Data for Figure 4c [30kB]

Data for Supplementary Fig 11b [28kB]

Consurf Outputs for Supplementary Figure 13 [1MB]

Data for Supplementary Fig 15b [27kB]

Data for Supplementary Fig 15c [29kB]

Data for Supplementary Figure 16 [44kB]

NMR data for Supplementary Figure 8a [3MB]

Data for Supplementary Fig 9 [437kB]

Data for Supplementary Figure 16 [87kB]

Data for Supplementary Figure 17b [21kB]

Data for Supplementary Table 1 [6kB]

NMR data for Supplementary Figure 11 [63MB]

Data for Supplementary Figure 4 [45kB]

Data for Supplementary Figures 6 and 7 [667kB]