Research Data Leeds Repository

Encapsulation of Microbubbles within Folded Protein Hydrogels: Effects on the mechanical and structural properties

Citation

Brown, Christa P. and Hughes, Matt D. G. and Mahmoudi, Najet and Brockwell, David J. and Coletta, P. Louise and Peyman, Sally A. and Evans, Stephen D. and Dougan, Lorna (2023) Encapsulation of Microbubbles within Folded Protein Hydrogels: Effects on the mechanical and structural properties. University of Leeds. [Dataset] https://doi.org/10.5518/1212¹

Dataset description

The data covers a study of folded protein hydrogel with embedded microbubbles, and their examination using rheology, small angle scattering and microscopy.

Keywords:	Protein, mechanics, hydrogels, biomaterials, structure, microbubbles, SANS, rheology
Subjects:	C000 - Biological sciences > C100 - Biology2 C000 - Biological sciences > C700 - Molecular biology, biophysics & biochemistry3 F000 - Physical sciences > F100 - Chemistry4 F000 - Physical sciences > F300 - Physics5
Divisions:	Faculty of Engineering and Physical Sciences > School of Physics and Astronomy6
Related resources:	Location Type https://doi.org/10.1039/d2bm01918c7 Publication https://eprints.whiterose.ac.uk/199478/8 Publication
License:	Creative Commons Attribution 4.0 International (CC BY 4.0)
Date deposited:	22 Feb 2023 10:49
URI:	https://archive.researchdata.leeds.ac.uk/id/eprint/10749
Additional details Additional details Creators or authors: Creators ORCID Other ID Email Primary affiliation Primary affiliation ID Primary affiliation ID type Secondary affiliation Secondary affiliation ID Secondary affiliation ID type Brown, Christa P. https://orcid.org/0000-0002-6551-395310 University of Leeds https://ror.org/024mrxd33 ror Hughes, Matt D. G. https://orcid.org/0000-0001-5838-793911 University of Leeds https://ror.org/024mrxd33 ror Mahmoudi, Najet https://orcid.org/0000-0003-4936-691112 University of Leeds https://ror.org/024mrxd33 ror Brockwell, David J. https://orcid.org/0000-0002-0802-593713 University of Leeds https://ror.org/024mrxd33 ror Coletta, P. Louise https://orcid.org/0000-0002-3858-607314 University of Leeds https://ror.org/024mrxd33 ror Peyman, Sally A. https://orcid.org/0000-0002-1600-510015 University of Leeds https://ror.org/024mrxd33 ror Evans, Stephen D. https://orcid.org/0000-0001-8342-533516 University of Leeds https://ror.org/024mrxd33 ror Dougan, Lorna https://orcid.org/0000-0002-2620-582717 University of Leeds https://ror.org/024mrxd33 ror Type of data: Dataset Research funders: Alumni Leeds,Margaret Steel Award, NIHR, EPSRC Grant numbers: n/a, EPP023266/1, EP/S001069/1, EP/W033151/1, EP/P02288X/1 Publication date: 2023 Resource language: English Metadata language: English Publisher: University of Leeds Contact email: py14cpb@leeds.ac.uk18 Last Modified: 02 Sep 2024 12:31

Files

Data

Circular Dichroism [64kB] 19 Circular Dichroism [64kB] 20 Circular Dichroism [64kB] 21 Security: Anyone File name: circular_dichroism.zip22 Content type: Data Description: circular dichroism data for pre and post gelation of BSA hydrogels, in the absence and presence of microbubbles Mime-Type: application/zip License: Creative Commons Attribution 4.0 International (CC BY 4.0) File size: 64kB

MB concentration in solution and in BSA hydrogel [4GB] 23 MB concentration in solution and in BSA hydrogel [4GB] 24 MB concentration in solution and in BSA hydrogel [4GB] 25 Security: Anyone File name: microbubble_concentrations.zip26 Content type: Data Mime-Type: application/zip License: Creative Commons Attribution 4.0 International (CC BY 4.0) File size: 4GB

Ultrasound on microbubbles in BSA hydrogel [7MB] 27 Ultrasound on microbubbles in BSA hydrogel [7MB] 28 Ultrasound on microbubbles in BSA hydrogel [7MB] 29 Security: Anyone File name: Ultrasound_bursting_microbubbles.zip30 Content type: Data Description: Images of the BSA hydrogel before and after ultrasound Mime-Type: application/zip License: Creative Commons Attribution 4.0 International (CC BY 4.0) File size: 7MB

cross-linking quantification [44kB] 31 cross-linking quantification [44kB] 32 cross-linking quantification [44kB] 33 Security: Anyone File name: dityrosine_emission.xlsx34 Content type: Data Description: Data of the dityrosine emission from BSA hydrogels, comparing ithe emission in the abscence and presence of microbubbles Mime-Type: application/vnd.openxmlformats-officedocument.spreadsheetml.sheet License: Creative Commons Attribution 4.0 International (CC BY 4.0) File size: 44kB

microbubble trajectories [43kB] 35 microbubble trajectories [43kB] 36 microbubble trajectories [43kB] 37 Security: Anyone File name: microbubble_trajectories.xlsx38 Content type: Data Description: trajectories of the movement of microbubbles through BSA hydrogel compared to buffer solution Mime-Type: application/vnd.openxmlformats-officedocument.spreadsheetml.sheet License: Creative Commons Attribution 4.0 International (CC BY 4.0) File size: 43kB

Rheological characterisation [3MB] 39 Rheological characterisation [3MB] 40 Rheological characterisation [3MB] 41 Security: Anyone File name: rheology.xlsx42 Content type: Data Description: TimeSweep data for the gelation curves, frequency sweep, stress-strain curves and non-linear behaviour Mime-Type: application/vnd.openxmlformats-officedocument.spreadsheetml.sheet License: Creative Commons Attribution 4.0 International (CC BY 4.0) File size: 3MB

• 1. https://doi.org/10.5518/1212
• 2. https://archive.researchdata.leeds.ac.uk/view/subjects/C100.html
• 3. https://archive.researchdata.leeds.ac.uk/view/subjects/C700.html
• 4. https://archive.researchdata.leeds.ac.uk/view/subjects/F100.html
• 5. https://archive.researchdata.leeds.ac.uk/view/subjects/F300.html
• 6. https://archive.researchdata.leeds.ac.uk/view/divisions/SPA/
• 7. https://doi.org/10.1039/d2bm01918c
• 8. https://eprints.whiterose.ac.uk/199478/
• 9. https://archive.researchdata.leeds.ac.uk/id/eprint/1074
• 10. https://orcid.org/0000-0002-6551-3953
• 11. https://orcid.org/0000-0001-5838-7939
• 12. https://orcid.org/0000-0003-4936-6911
• 13. https://orcid.org/0000-0002-0802-5937
• 14. https://orcid.org/0000-0002-3858-6073
• 15. https://orcid.org/0000-0002-1600-5100
• 16. https://orcid.org/0000-0001-8342-5335
• 17. https://orcid.org/0000-0002-2620-5827
• 18. mailto:py14cpb@leeds.ac.uk
• 19. https://archive.researchdata.leeds.ac.uk/1074/1/circular_dichroism.zip
• 20. https://archive.researchdata.leeds.ac.uk/1074/1/circular_dichroism.zip
• 21. https://archive.researchdata.leeds.ac.uk/1074/1/circular_dichroism.zip
• 22. https://archive.researchdata.leeds.ac.uk/1074/1/circular_dichroism.zip
• 23. https://archive.researchdata.leeds.ac.uk/1074/6/microbubble_concentrations.zip
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• 25. https://archive.researchdata.leeds.ac.uk/1074/6/microbubble_concentrations.zip
• 26. https://archive.researchdata.leeds.ac.uk/1074/6/microbubble_concentrations.zip
• 27. https://archive.researchdata.leeds.ac.uk/1074/2/Ultrasound_bursting_microbubbles.zip
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• 30. https://archive.researchdata.leeds.ac.uk/1074/2/Ultrasound_bursting_microbubbles.zip
• 31. https://archive.researchdata.leeds.ac.uk/1074/3/dityrosine_emission.xlsx
• 32. https://archive.researchdata.leeds.ac.uk/1074/3/dityrosine_emission.xlsx
• 33. https://archive.researchdata.leeds.ac.uk/1074/3/dityrosine_emission.xlsx
• 34. https://archive.researchdata.leeds.ac.uk/1074/3/dityrosine_emission.xlsx
• 35. https://archive.researchdata.leeds.ac.uk/1074/4/microbubble_trajectories.xlsx
• 36. https://archive.researchdata.leeds.ac.uk/1074/4/microbubble_trajectories.xlsx
• 37. https://archive.researchdata.leeds.ac.uk/1074/4/microbubble_trajectories.xlsx
• 38. https://archive.researchdata.leeds.ac.uk/1074/4/microbubble_trajectories.xlsx
• 39. https://archive.researchdata.leeds.ac.uk/1074/5/rheology.xlsx
• 40. https://archive.researchdata.leeds.ac.uk/1074/5/rheology.xlsx
• 41. https://archive.researchdata.leeds.ac.uk/1074/5/rheology.xlsx
• 42. https://archive.researchdata.leeds.ac.uk/1074/5/rheology.xlsx