Data set associated with “An experimental simulation model to assess wear of the porcine patellofemoral joint”. The dataset contains material to supplement the paper “An experimental simulation model to assess wear of the porcine patellofemoral joint” including: ICRS cartilage score of the patella and femur after 3 hours wear simulation, the wear volume, deformation and damage of the cartilage on the femoral trochlear after 3 hours wear simulation, the protrusion of the pin/osteochondral graft from the cartilage surface pre- and post-test, further analysis of the wear scars in the femoral trochlear and height maps showing the position of the osteochondral grafts pre- and post-test taken from Accutrans replicas of the cartilage surfaces. The aim of this study was to develop an experimental simulation model to pre-clinically assess and predict the wear of osteochonal allografts in the natural porcine patellofemoral joint.