This dataset contains the diffusion eigenvectors derived from the DT-MRI images of the cartilage sample investigated in this study, the finite element model developed based on the diffusion eigenvectors, and the outputs of the finite element models presented in the paper. Further details of the methods and results can be found in the paper (10.1016/j.jmbbm.2016.09.001). The files correspond to the figures in the paper as follows: 1_DTMRI_Eigenvectors.zip - Figures 2 and 3. 2_DTMRI_JMBBM_Model1.feb - Results of Model 1 presented in Figures 4 to 11. ("feb" format is for FEBio) 3_Fluid_load_support.xlsx - Figure 5. 4_Comparison_stress_strain.xlsx - Figures 6(k) to 11(k).