This dataset corresponds to the Raman data for the paper: J. Gala de Pablo, D. R. Chisholm, A. Steffen, A. K. Nelson, C. Mahler, T. B. Marder, S. A. Peyman, J. M. Girkin, C. A. Ambler, A. Whiting and S. D. Evans, Anal., DOI:10.1039/C8AN01461B. The data included corresponds to single point spectra with both 785 and 532 nm lasers, and of maps for a control cell and a cell incubated with DC473. The pre-processed data has also been included, prepared as described in the paper methods. Corresponding author: Stephen Evans, S.D.Evans@leeds.ac.uk Principal Investigator: Julia Gala de Pablo, py12jg@leeds.ac.uk