1. ABOUT THE DATASET
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Title: Data Associated with 'Injection Volume Is a Better Predictor of Stiffness Restoration Than Injection Force in an In Vitro Study of Nucleus Augmentation of the Intervertebral Disc' 	

Creator(s): Warren JP [1], Mengoni M [1], Wilcox RK [1].

Organisation(s): 1. University of Leeds. 

Rights-holder(s):Unless otherwise stated, Copyright 2025 University of Leeds

Publication Year: 2025

Description: Data from a biomechanical study of spinal nucleus augmentation with a self-assembling hydrogel. The biomechanical data was acquired during in vitro testing of bovine tail specimens in a native, artificially degenerated, and treated states. 

Cite as: Warren JP, Mengoni M, Wilcox RK. 2025. Data Associated with Injection Volume Is a Better Predictor of Stiffness Restoration Than Injection Force in an In Vitro Study of Nucleus Augmentation of the Intervertebral Disc. [Dataset] https://doi.org/10.5518/1712

Related publication: Warren JP, Dixon AR, Culbert MP, Khan A, Mengoni M, Wilcox RK. Injection Volume Is a Better Predictor of Stiffness Restoration Than Injection Force in an In Vitro Study of Nucleus Augmentation of the Intervertebral Disc. JOR Spine. 2025 Jun 10;8(2):e70081. doi: 10.1002/jsp2.70081. PMID: 40496969; PMCID: PMC12149600.

Contact: r.k.wilcox@leeds.ac.uk


2. TERMS OF USE
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Copyright 2025, University of Leeds. Unless otherwise stated, this dataset is licensed under a Creative Commons Attribution 4.0 International Licence: https://creativecommons.org/licenses/by/4.0/.]


3. PROJECT AND FUNDING INFORMATION
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Title: Unuversity of Leeds DTP 

Dates: 2018-2023

Funding organisation: EPSRC (Engineerng and Physical Sciences Research Council UK) 

Grant no.: EP/R513258/1

4. CONTENTS
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File listing

SummaryData.csv
This contains the core processed biomechanical data, used in the results presented in Figure 2b, Figure 4, Table 1 and in the text of the publication.

Figure1.tiff
A high resolution version of Figure 1

Figure2a_ExampleDataset.csv
Typical stiffness data acquired over 1000 cycles in each of the three stages of testing. This data was used for Figure 2a.

Figure2c_ExampleDataset.csv
Typical force-time data acquired during the nucleus injection process. This data was used for Figure 2c.

Figure3_***.PNG
High resolution versions of each of the CT slices shown in Figure 3.

Folder: Injection force time data
T0**_D*_Injection.csv
Force time data taken during the injection of each specimen
 

5. METHODS
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The detailed methods are provided in the associated publication.