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Dataset for a randomised factorial experiment to optimise an information leaflet for women with breast cancer

Citation

Green, Sophie M. C. and Smith, Samuel G. (2024) Dataset for a randomised factorial experiment to optimise an information leaflet for women with breast cancer. University of Leeds. [Dataset] https://doi.org/10.5518/1467

This item is part of the Optimization of an information leaflet to support medication adherence in breast cancer collection.

Dataset description

Most women with breast cancer are prescribed adjuvant endocrine therapy (AET) to prevent recurrence and mortality, but adherence is low. Negative beliefs about the necessity of AET and high concerns are barriers to adherence. We aimed to optimize the content of an information leaflet intervention, to support AET beliefs. We conducted an online screening experiment using a 2^5 factorial design to optimize the leaflet. The leaflet had five candidate components, each operationalised as factors with two levels; 1) diagrams about AET mechanisms (on/off); 2) infographics displaying AET benefits (enhanced/basic); 3) AET side-effects (enhanced/basic); 4) answers to AET concerns (on/off); 5) breast cancer survivor (patient) input: quotes and photographs (on/off). Healthy adult women (n=1604), recruited via a market research company, were randomized to one of 32 experimental conditions, which determined the combination of components received. Participants completed the beliefs about medicines questionnaire before and after viewing the leaflet. After viewing the leaflet, participants also completed a modified version of the satisfaction with information about medicines questionnaire to assess their satisfaction with information received about AET, and eight true/false questions about AET, to assess their knowledge about AET after reading the leaflet.

Additional information: This dataset is not publicly available. Click the link under ‘Related resources’ to request access via the RADAR Restricted Access Data Repository. You will be asked to complete a request form explaining why you need access to the data. You will receive an initial response to your request within 5 working days.
Keywords: breast cancer, medication beliefs, optimization, factorial, information leaflet
Subjects: A000 - Medicine & dentistry
Divisions: Faculty of Medicine and Health > School of Medicine > Leeds Institute of Health Sciences (LIHS)
Related resources:
LocationType
https://radar.researchdata.leeds.ac.uk/55/Dataset
https://doi.org/10.1093/tbm/ibae029Publication
https://doi.org/10.3310/nihropenres.13547.1Publication
https://eprints.whiterose.ac.uk/212205/Publication
License: Creative Commons Attribution 4.0 International (CC BY 4.0)
Date deposited: 14 May 2024 06:51
URI: https://archive.researchdata.leeds.ac.uk/id/eprint/1278

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