1. ABOUT THE DATASET
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Title: Dataset for the Independent Experimental Calibration and Validation of Finite Element Models of Osteochondral Grafts in Tibiofemoral Joints
Creator(s): Gavin A Day, Alison C Jones, Marlène Mengoni, Ruth K Wilcox

Organisation(s): Institute of Medical and Biological Engineering, University of Leeds, Leeds, UK

Rights-holder(s): University of Leeds

Publication Year:2023

Description: This dataset includes experimental data, three dimensional uCT image data, computational models and results from an associated study entitled: A Finite Element Model to Investigate the Stability of Osteochondral Grafts within a Human Tibiofemoral Joint. Specifically, the dataset includes packages of work from three parallel, experimental and computational pieces of work: a material property calibration study, a frictional force/ osteochondral graft push-in study and a tibiofemoral knee joint study. Each of these three include uCT scan data for the human knee specimens used, specimen specific finite element model input files for Abaqus and experimental and computational results.


Cite as: Day GA, Jones AC, Mengoni M, Wilcox RK. (2023): Dataset for the Independent Experimental Calibration and Validation of Finite Element Models of Osteochondral Grafts in Tibiofemoral Joints. University of Leeds. [Dataset] https://doi.org/10.5518/1387

Related publication: Day GA, Jones AC, Mengoni M, Wilcox RK. A Finite Element Model to Investigate the Stability of Osteochondral Grafts within a Human Tibiofemoral Joint (Under Review)
Also:
Robert J. Cooper, Gavin A. Day, Vithanage N. Wijayathunga, Jiacheng Yao, Marlène Mengoni, Ruth K. Wilcox, Alison C. Jones. ‘Human tibiofemoral joint finite element model validation study: effect of cartilage thickness variation and assessment of precision’ (In preparation). 
Robert J. Cooper, Aiqin Liu, Gavin A. Day, Vithanage N. Wijayathunga, Louise M. Jennings, Ruth K. Wilcox, Alison C. Jones. ‘Development of robust finite element models of porcine tibiofemoral joints loaded under varied flexion angles and tibial freedoms’ Journal of the Mechanical Behavior of Biomedical Materials, 2020, 109:103797.

The data packets are all associated with the collection: https://doi.org/10.5518/826

Ethical approval: Ethical approval was obtained via East Midlands - Leicester South Research Ethics Committee (18/EM/0224) for the use of fresh-frozen human cadaveric knees in this work.

Contact: Gavin A. Day  g.day1@leeds.ac.uk


2. TERMS OF USE
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 Copyright 2023 University of Leeds. This dataset is licensed under a Creative Commons Attribution 4.0 International Licence: https://creativecommons.org/licenses/by/4.0/.


3. PROJECT AND FUNDING INFORMATION
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Title: Optimising knee therapies through improved population stratification and precision of the intervention

Dates: 01 Oct 2016 - 30 Sep 2022

Funding organisation:  EPSRC

Grant no.: EP/P001076/1

4. CONTENTS
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File listing
1. Material Property Calibration Data
	a) Experimental and compuational stiffness results for the material property calibration study.
		└─── Material_Property_OptimisationExperimental_Computational_Stiffness_Results.csv
	b) Scan Data for the six condyles, from three human knees
		├─── Material_Property_Optimisation_ScanData_LTKN9164_condyle.zip
		├─── Material_Property_Optimisation_ScanData_LTKN9347_condyle.zip
		└─── Material_Property_Optimisation_ScanData_RTKN2741_condyle.zip
	c) Specimen specific Finite Element Abaqus input files
		└─── Material_Property_Optimisation_Abaqus_INP_model_files.zip
2. Push-in Test / Frictional Calibration Study
   	a) Experimental Data and compuational callibration results
		├─── Push-in_Force_Displacement_Results.xlsx
		└─── Push-in_Test_Friction_Calibration_Results.xlsx
	b) Scan Data
		├─── Push-in_Test_Friction_Calibration_ScanData_LTKN6046.zip
		└─── Push-in_Test_Friction_Calibration_ScanData_LTKN6063.zip
	c) Specimen specific Finite Element Abaqus input files
		└─── Push-in_Test_Friction_Calibration_Host_and_Osteochondral_Graft_Model.zip
				├─── LTKN6046
				└─── LTKN6063
3. Tibiofemoral Knee Joint Study
	a) Scan Data
		├───Tibiofem_ScanData_LTKN8941_Post_Test_Scan_Data.zip
		├───Tibiofem_ScanData_LTKN8941_Pre_test_Femur_Only.zip
		└───Tibiofem_ScanData_LTKN8941_Pre_Test_Scan_Data_Joint.zip
	b) Tibiofem Experimental Contact Data
		└─── Tibiofem_Experimental_Contact_Data.zip
	c) Specimen specific Finite Element Abaqus input files
		└───Tibiofem_Computational_Models.zip
				├───Graft
				├───Hole
				└───Intact


5. METHODS
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All uCT scans were captured using a HR-pQCT, XtremeCT, Scanco Medical AG, Switzerland; 82 µm isotropic voxel size: 900 lA, 60 kVp energy and 300 ms exposure time.
Specific Finite element modelling methods can be found in the Finite Element Modelling Methodology document FiniteElementModellingMethodology.txt
The remaining methods are described in full in the associated journal publication: Day GA, Jones AC, Mengoni M, Wilcox RK. A Finite Element Model to Investigate the Stability of Osteochondral Grafts within a Human Tibiofemoral Joint (Under Review).