Research Data Leeds Repository

Citation

Mancinelli, Elena and Zushi, Nanami and Takuma, Megumi and Chau, Chalmers C. and Parpas, George and Fujie, Toshinori and Pensabene, Virginia (2024) Data for 'Porous polymeric nanofilms for recreating the basement membrane in an endothelial barrier-on-chip'. University of Leeds. [Dataset] https://doi.org/10.5518/1473

Dataset description

The dataset contains all relevant pictures, AFM scans, Young Modulus related data, z-stacks confocal images, flurescence data releted to permeability experiments and Trans Endothelial Electrical Resistance measurments for the associated paper entitled "Porous polymeric nanofilms for recreating the basement membrane in an endothelial barrier-on-chip". All graphs originated from images or AFM scans can be reproduced following the relevant method section in the associated pubblication. The dataset is aimed at allowing users to re-analyze the data and reproduce the observations made in the associated publication.

Keywords:	AFM scans, heigh profiles, Young Modulus, viability assay, permeability assay, TEER, z stacks
Subjects:	H000 - Engineering > H600 - Electronic & electrical engineering
Divisions:	Faculty of Engineering and Physical Sciences > School of Electronic and Electrical Engineering
Related resources:	Location Type https://doi.org/10.1021/acsami.3c16134 Publication https://eprints.whiterose.ac.uk/213636/ Publication
License:	Creative Commons Attribution 4.0 International (CC BY 4.0)
Date deposited:	26 Jan 2024 14:11
URI:	https://archive.researchdata.leeds.ac.uk/id/eprint/1229
Additional details Additional details Creators or authors: Creators ORCID Other ID Email Primary affiliation Primary affiliation ID Primary affiliation ID type Secondary affiliation Secondary affiliation ID Secondary affiliation ID type Mancinelli, Elena https://orcid.org/0000-0002-0530-1924 University of Leeds https://ror.org/024mrxd33 ror Zushi, Nanami Tokyo Institute of Technology https://ror.org/0112mx960 ror Takuma, Megumi Tokyo Institute of Technology https://ror.org/0112mx960 ror Chau, Chalmers C. https://orcid.org/0000-0002-3134-6798 University of Leeds https://ror.org/024mrxd33 ror Parpas, George University of Leeds https://ror.org/024mrxd33 ror Fujie, Toshinori https://orcid.org/0000-0003-1417-8670 Tokyo Institute of Technology https://ror.org/0112mx960 ror Pensabene, Virginia https://orcid.org/0000-0002-3352-8202 University of Leeds https://ror.org/024mrxd33 ror Type of data: Dataset Research funders: JST FOREST, JSPS KAKENHI, Faculty of Engineering and Physical Science International Mobility Fund at the University of Leeds, European Union’s Horizon 2020 research and innovation 7 program under the Marie Skłodowska-Curie MSCA-ITN grant agreement no. 812 Grant numbers: JPMJFR203Q, 21H03815, 812398, MR/N013840/1, EP/W004933/1 Publication date: 2024 Resource language: English Metadata language: English Publisher: University of Leeds Contact email: V.pensabene@leeds.ac.uk Last Modified: 02 Sep 2024 12:14

Files

Data

Figure_2 [282MB] Figure_2 [282MB] Figure_2 [282MB] Security: Anyone File name: Figure_2.zip Content type: Data Description: Data and AFM scans for Figure 2 Mime-Type: application/zip License: Creative Commons Attribution 4.0 International (CC BY 4.0) File size: 282MB

Figure_3 [1GB] Figure_3 [1GB] Figure_3 [1GB] Security: Anyone File name: Figure_3.zip Content type: Data Description: Nuclei and F-Actin images for Figure 3 Mime-Type: application/zip License: Creative Commons Attribution 4.0 International (CC BY 4.0) File size: 1GB

Figure_4 [19kB] Figure_4 [19kB] Figure_4 [19kB] Security: Anyone File name: Figure_4.zip Content type: Data Description: Data for Figure 4 Mime-Type: application/zip License: Creative Commons Attribution 4.0 International (CC BY 4.0) File size: 19kB

Figure_5 [258MB] Figure_5 [258MB] Figure_5 [258MB] Security: Anyone File name: Figure_5.zip Content type: Data Description: Confocal z-stacks for Figure 5 Mime-Type: application/zip License: Creative Commons Attribution 4.0 International (CC BY 4.0) File size: 258MB

Figure_6 [62MB] Figure_6 [62MB] Figure_6 [62MB] Security: Anyone File name: Figure_6.zip Content type: Data Description: Confocal z-stacks and images for Figure 6 Mime-Type: application/zip License: Creative Commons Attribution 4.0 International (CC BY 4.0) File size: 62MB

Figure_S4 [89MB] Figure_S4 [89MB] Figure_S4 [89MB] Security: Anyone File name: Figure_S4.zip Content type: Data Description: AFM scans for Figure S4 (Supplementary) Mime-Type: application/zip License: Creative Commons Attribution 4.0 International (CC BY 4.0) File size: 89MB

Figure_S5 [308kB] Figure_S5 [308kB] Figure_S5 [308kB] Security: Anyone File name: Figure_S5.zip Content type: Data Description: Height profile for Figure S5 (Supplementary) Mime-Type: application/zip License: Creative Commons Attribution 4.0 International (CC BY 4.0) File size: 308kB

Figure_S6 [134MB] Figure_S6 [134MB] Figure_S6 [134MB] Security: Anyone File name: Figure_S6.zip Content type: Data Description: AFM scans for Figure S6 (Supplementary) Mime-Type: application/zip License: Creative Commons Attribution 4.0 International (CC BY 4.0) File size: 134MB

Figure_S7 [5MB] Figure_S7 [5MB] Figure_S7 [5MB] Security: Anyone File name: Figure_S7.zip Content type: Data Description: Contact angle data and images for Figure S7 (Supplementary) Mime-Type: application/zip License: Creative Commons Attribution 4.0 International (CC BY 4.0) File size: 5MB

Figure_S8 [150MB] Figure_S8 [150MB] Figure_S8 [150MB] Security: Anyone File name: Figure_S8.zip Content type: Data Description: Nuclei images for LIVE/DEAD assay in Figure S8 (Spplementary) Mime-Type: application/zip License: Creative Commons Attribution 4.0 International (CC BY 4.0) File size: 150MB

Figure_S9 [201MB] Figure_S9 [201MB] Figure_S9 [201MB] Security: Anyone File name: Figure_S9.zip Content type: Data Description: Confocal z-stacks for Figure S9 (Supplemtary) Mime-Type: application/zip License: Creative Commons Attribution 4.0 International (CC BY 4.0) File size: 201MB