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A factorial randomised trial investigating factors influencing general practitioners’ willingness to prescribe aspirin for cancer preventive therapy in Lynch syndrome: a registered report

Citation

Lloyd, Kelly E. and Hall, Louise H. and Ziegler, Lucy and Foy, Robbie and Borthwick, Gillian M. and MacKenzie, Mairead and Taylor, David G. and Smith, Samuel G., AsCaP group (2022) A factorial randomised trial investigating factors influencing general practitioners’ willingness to prescribe aspirin for cancer preventive therapy in Lynch syndrome: a registered report. University of Leeds. [Dataset] https://doi.org/10.5518/1184

Dataset description

We investigated the optimal type and level of information to communicate with GPs to increase willingness to prescribe aspirin for colorectal cancer prevention. We recruited GPs in England and Wales (n=672) to an online survey with a 2 by 3 factorial design. GPs were randomised to one of eight vignettes describing a hypothetical patient with Lynch syndrome recommended to take aspirin by a clinical geneticist. Across the vignettes, we manipulated the presence or absence of three types of information: 1) existence of NICE guidance; 2) results from the CAPP2 trial; 3) information comparing risks/benefits of aspirin. We estimated the main effects and all interactions on the primary (willingness to prescribe) and secondary outcomes (comfort discussing aspirin).

Keywords: Preventive therapy; chemoprevention; decision-making; primary care; aspirin; NSAID
Subjects: C000 - Biological sciences > C800 - Psychology > C840 - Psychology in health & medicine
Divisions: Faculty of Medicine and Health > School of Medicine
Related resources:
LocationType
https://doi.org/10.3399/BJGP.2021.0610Publication
https://eprints.whiterose.ac.uk/194496/Publication
https://etheses.whiterose.ac.uk/32715/Ethesis
License: Creative Commons Attribution 4.0 International (CC BY 4.0)
Date deposited: 15 Aug 2022 14:22
URI: https://archive.researchdata.leeds.ac.uk/id/eprint/1009

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