Research Data Leeds Repository

A factorial randomised trial investigating factors influencing general practitioners’ willingness to prescribe aspirin for cancer preventive therapy in Lynch syndrome: a registered report

Lloyd, Kelly E. and Hall, Louise H. and Ziegler, Lucy and Foy, Robbie and Borthwick, Gillian M. and MacKenzie, Mairead and Taylor, David G. and Smith, Samuel G., AsCaP group (2022) A factorial randomised trial investigating factors influencing general practitioners’ willingness to prescribe aspirin for cancer preventive therapy in Lynch syndrome: a registered report. University of Leeds. [Dataset] https://doi.org/10.5518/1184

Dataset description

We investigated the optimal type and level of information to communicate with GPs to increase willingness to prescribe aspirin for colorectal cancer prevention. We recruited GPs in England and Wales (n=672) to an online survey with a 2 by 3 factorial design. GPs were randomised to one of eight vignettes describing a hypothetical patient with Lynch syndrome recommended to take aspirin by a clinical geneticist. Across the vignettes, we manipulated the presence or absence of three types of information: 1) existence of NICE guidance; 2) results from the CAPP2 trial; 3) information comparing risks/benefits of aspirin. We estimated the main effects and all interactions on the primary (willingness to prescribe) and secondary outcomes (comfort discussing aspirin).

Keywords:	Preventive therapy; chemoprevention; decision-making; primary care; aspirin; NSAID
Subjects:	C000 - Biological sciences > C800 - Psychology > C840 - Psychology in health & medicine
Divisions:	Faculty of Medicine and Health > School of Medicine
License:	Creative Commons Attribution 4.0 International (CC BY 4.0)
Date deposited:	15 Aug 2022 14:22
URI:	http://archive.researchdata.leeds.ac.uk/id/eprint/1009
Additional details Additional details Creators: Creators ORCID Other ID Email Primary affiliation Primary affiliation ID Primary affiliation ID type Secondary affiliation Secondary affiliation ID Secondary affiliation ID type Lloyd, Kelly E. https://orcid.org/0000-0002-0420-2342 University of Leeds https://ror.org/024mrxd33 ror Hall, Louise H. https://orcid.org/0000-0001-9032-4540 University of Leeds https://ror.org/024mrxd33 ror Ziegler, Lucy https://orcid.org/0000-0001-9563-5014 University of Leeds https://ror.org/024mrxd33 ror Foy, Robbie https://orcid.org/0000-0003-0605-7713 University of Leeds https://ror.org/024mrxd33 ror Borthwick, Gillian M. Newcastle University MacKenzie, Mairead Independent Cancer Patients’ Voice (ICPV) Taylor, David G. https://orcid.org/0000-0003-0679-1467 UCL Smith, Samuel G. https://orcid.org/0000-0003-1983-4470 University of Leeds https://ror.org/024mrxd33 ror Corporate creators: AsCaP group Type of data: Dataset Research funders: CRUK, ESRC, NIHR Grant numbers: A24991, ES/P000745/1, NIHR300588 Publication date: 2022 Resource language: English Publisher: University of Leeds Contact Email Address: umkel@leeds.ac.uk Last Modified: 15 Aug 2022 22:35

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Documentation

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Data

Study materials [554kB] Study materials [554kB] Study materials [554kB] Visible to: Anyone File name: Study_materials.zip Content type: Data Mime-Type: application/zip License: Creative Commons Attribution 4.0 International (CC BY 4.0) File size: 554kB

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Clean data [40kB] Clean data [40kB] Clean data [40kB] Visible to: Anyone File name: Clean_data.zip Content type: Data Description: Final cleaned dataset, which is the raw dataset after all R scripts have been applied to it Mime-Type: application/zip License: Creative Commons Attribution 4.0 International (CC BY 4.0) File size: 40kB